Ointments with antibacterial, wound healing and anti-inflammatory effects are widely used in modern medicine, because many diseases that appear on the skin require complex treatment – internal medication and external treatment.
Lokoid – composition
Ointment Lokoid has a simple composition – only one active ingredient – hydrocortisone. In 1 g of the drug it contains 1 mg.
Also in the ointment there are auxiliary agents – vaseline oil – 95% and polyethylene – 5%.
The product is produced in aluminum tubes.
The ointment has a concentration of 0.1% and looks translucent with a light gray tint.
Lokoid ointment – hormonal or not?
Since the main active ingredient of the ointment is hydrocortisone, we can say that the ointment is hormonal.
Pharmacological action of Locoid ointment
Lokoid ointment has a wide range of effects on tissues – hydrocortisone inhibits the functions of leukocytes and macrophages that are involved in the inflammatory process. This substance does not let leukocytes into the area of inflammation, and therefore the manifestation of inflammation is reduced.
The ointment has a decongestant, antipruritic, anti-inflammatory effect.
With systemic use, a lasting effect is observed, but at the same time, it is not recommended to use hydrocortisone regularly – the hormones of the adrenal cortex, the analogue of which is hydrocortisone, are sensitive to the ingestion of hormone analogues, and therefore addiction to the medication may occur over time.
Ointment Lokoid is a method of symptomatic treatment, and it often does not solve the true problem of the disease.
It is also worth considering that hydrocortisone has an immunosuppressive effect – it suppresses the immune system, and therefore is not very effective for treating a number of diseases caused by viral lesions.
Ointment Lokoid, in addition to anti-inflammatory, anti-edematous and antipruritic action, promotes accelerated healing of tissues. It has a drying effect, which is useful for open injuries.
Application of ointment Lokoid
Locoid ointment is used externally – it is necessary to apply applications to the affected areas in a thick layer 1-3 times a day.
Locoid accumulates in the epidermis and therefore it is important to use it systemically. The active substance is absorbed into the blood, but after discontinuation of the drug, it is excreted within a few days through the intestines.
What to choose – Lokoid ointment or cream?
Lokoid ointment, unlike Lokoid cream, is more effective, since the ointment is in contact with the skin for a long time.
Ointment Lokoid during pregnancy
Ointment Lokoid is forbidden to use during pregnancy, if it does not pose a threat to the life of the mother. The active substance crosses the placental barrier, and therefore the effect on the fetus can be pronounced.
There is no data on how much hydrocortisone is found in breast milk when using the ointment, but the use of this medication should also be avoided during lactation.
If Lokoid is applied to large areas of the skin during pregnancy, this can lead to a particularly pronounced effect of hydrocortisone on the fetus.
Ointment Lokoid – indications for use
Locoid is used to treat non-infectious skin diseases:
- with eczema;
- with psoriasis;
- with dermatitis – atopic, seborrheic, contact.
Contraindications to the use of Lokoid ointment
Lokoid is forbidden to use for the treatment of the following diseases:
- fungal infections of the skin;
- parasitic infections of the skin;
- bacterial skin infections;
- viral infections of the skin;
- tuberculous skin infections;
- syphilitic lesions;
- post-vaccination period;
- benign or malignant tumors;
- wounds and ulcers;
- allergic reaction to the active substance;